The Basics:

Osteochondrosis desicans (OCD) is a juvenile bone disease.  It occurs when there is a problem in the growth of an area of cartilage.  It is known to be strongly heritable and is generally a problem in large breeds of dogs and horses.                      
OCD lesions can occur in multiple joints.  It is not uncommon to find more than one joint involved.   OCD can be found in the stifle (knee) joint, tarsal (hock) joint, elbow joint, and commonly in the shoulder joint.

 

Clinical signs:

 

The clinical signs of OCD are usually subtle but may be dramatic.  There is usually a mild, weight bearing, lameness.  It is commonly seen after exercise and may exhibit first thing in the morning or upon rousing from a rest.  Occasionally the diseased cartilage will break loose creating a "joint  mouse".   

If a joint mouse is present the animal may be non-weight bearing on the affected limb.

Since it is not uncommon for OCD to be found bilaterally (for example both hocks), it can be mistaken for other lameness such as hip dysplasia

Diagnosis:

 

Diagnosis is generally made by a combination of orthopedic exam, radiographs, and exploratory surgery.

As stated earlier, symptoms of OCD can be vague and similar to other orthopedic problems, which makes diagnosis by only examination difficult at best.

About half the time radiographs will show an OCD lesion.  Radiographs will also show secondary signs such as joint effusion.

In about 1/3 of the cases exploratory surgery of the joint is needed to verify a diagnosis. 

Treatment:

 

Treatment for OCD consists of surgical removal of any joint mice and curetting the area of the lesion.   Curetting involves removing any diseased cartilage and stimulating new fibrocartilage to replace it.

There is a high chance of developing degenerative joint disease (DJD) with OCD.  The DJD is treated with anti-inflammatory drugs  (such as Rimadyl®) and chondroprotective agents (such as Cosequin®).